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Kev tsis

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peptides

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Cov khoom lag luam

### Kev Tshawb Fawb Txog Kev Ntsuam Xyuas: Cov yam ntxwv molecular, cov ntawv thov thiab synergistic cuam tshuam ntawm bpc -157, GHK-CU thiab TB-500

#### ** QHIA **

Raws li bioactive molecules, peptides tau nyiam ntau saib rau hauv cov tshuaj, cov kab mob regenerat 4}} bpc-500 lub peev xwm . Cov kab ke ntawm kev tshawb fawb ntawm lub tshuab kev tshawb fawb, cov khoom siv txheeb, txheeb raws roj ntsha thiab cov ntawv thov kev kho mob.

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### *** {{1. bpc -157 (lub cev tiv thaiv compound -157) **

#### ** {{{1. molecular qauv thiab physicochemical khoom **

- ** Cov qauv molecular thiab molecular hnyav **: ib qho linear peptide muaj li ntawm-pro-gly-as-as-as-as-as-as-as-as-as-leu-Val.

- **Solubility**: Easily soluble in water (>50 mg / ml), me ntsis soluble hauv ethanol, tsis txhob muaj zog acid lossis muaj zog alkaline ib puag ncig .

- **Stability**: Most stable at pH 6-8, easy to degrade at high temperature (>40 degree) lossis ultraviolet hluav taws xob, pom zoo kom khaws cia hauv lub xeev qhuav ntawm {}} degree.

#### ** {2. xim thiab tsos **

- Dawb dawb lossis tawm-dawb-qhuav hmoov, tsis muaj impurities nag tam sim ntawd thaum lub siab purarent .

#### ** {{3. misiological kev ua si thiab qhov txiaj ntsig **

- ** Cov nqaij mos kho kom zoo nkauj

- ** anti-inflammolatory nyhuv **: inhibits tnf- thiab}}}}}}, relieves mob caj dab {}}

- ** Nowoproction **: tswj {5- ht thiab gaba tshuab, txhim kho kev puas tsuaj thiab ntxhov siab.

- **Safety**: No significant toxicity reported, median lethal dose (LD50)>10 mg / kg (nas) .

#### ** {4.} daim ntawv thov teb **

- Kho cov tshuaj kis las (kho cov kab mob ua kom haum), cov kab mob plab (mob plab zom mov (kho mob plab), ntsuas kev kho mob ntawm neurodegenerative {}}

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### ** {{2. GHK-CU (Tooj Peptide, Glycyl-hysine-Cu²⁺) **

#### ** {{{1. molecular qauv thiab physicochemical khoom **

- ** Cov qauv molecular thiab molecular hnyav **: Tripeptide complex (colecun₆o₄), molecular hnyav li 401 {}} ion, muaj tooj liab ion cov qauv celfate.

- ** Solubility **: Dej Zoo Solubility ({1}} Kuv), Yooj Yim Rau Precipite Tooj Liab Orgic in Acidic Ib puag ncig (Ph<5).

- ** STABLY **: nkag siab txog lub teeb, yuav tsum tau muab cia kom deb ntawm lub teeb; ruaj khov rau 6 lub hlis ntawm 4℃.

#### ** {2. xim thiab tsos **

- Vim tias tooj liab ions yog xiav xiav-ntsuab hmoov, cov lus yog pob tshab xiav, thiab cov xim xim qhia txog cov ntsiab lus tooj liab.

#### ** {{3. misiological kev ua si thiab qhov txiaj ntsig **

- ** Daim tawv nqaij rov ua dua tshiab ***

- ** antioxidant **: tshem tawm Ros thiab tiv thaiv cov hlwb los ntawm UV kev puas tsuaj .

- ** Kev tiv thaiv kab mob thiab tiv thaiv tsis tau tiv thaiv NF-κb txoj hauv kev thiab txo qis mob o {}}

- ** ** Npaj cov plaub hau loj hlob ntawm cov plaub hau cov plaub hau follices qia hlwb thiab txhim kho cov plaub hau poob.

#### ** {{4.} cov chaw thov **

- Kev tu cov tawv nqaij thiab kev tu tawv nqaij (tiv thaiv kev sib cav, kev kho cov plaub hau thiab kev kho cov plaub hau thiab mob ntev}

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### *** {{3. tb -500} (thymosin 4 nquag 4.

#### ** {{{1. molecular qauv thiab physicochemical khoom **

- ** Cov qauv molecular thiab molecular hnyav **: ib qho hluavtaws peptide muaj 43 amino acids, nrog txoj kab molecular, nrog txoj kab molecular ntawm 4963}}}}

- ** Solubility **: Qhov tsis muaj zog acidic tsis (acetic acid) yuav tsum muaj rau kev sib cais, thiab cov dej solubility yog tsis zoo .

- ** STABLY **: ruaj khov ntawm -20℃hauv lub thoob khov-qhuav hauv lub xeev khov, thiab yooj yim inactivated los ntawm kev rov qab khov thiab yaj yooj yim.

#### ** {2. xim thiab tsos **

- Cov hmoov dawb dawb lossis tawv dawb, tsis muaj xim thiab pob tshab tom qab kev sib cais ntawm cov siab heev .

#### ** {{3. misiological kev ua si thiab qhov txiaj ntsig **

- ** Cell tsiv teb chaws tsiv teb chaws **: Ua kom nrawm qhov kev tsiv teb tsaws ntawm fibroblasts thiab endothelial hlwb los ntawm g-actin binding .

- ** "Angiogenesis **: Txhim Kho Cov Ntshav Rau Ischemic Cov Ntsej Muag thiab raug siv rau kev kho mob myocardial infarction.

- ** Kev Tiv Thaiv Kev Tiv Thaiv ": Inhibits tgf - 1 thiab txo cov caws pliav txaus ntshai.

- ** Rov ua leeg rov qab **: txhim kho kev tawm dag zog ntev thiab txo ncua ncua rau cov leeg nqaij (doms).

#### ** {{4.} cov chaw thov **

- cov kab mob plawv (myocardial kho), kis mob kab mob (mob siab) kev cuam tshuam.

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### ** {{{4. synergistic cov nyhuv thiab sib piv ntawm peb **

#### ** {{1. sib piv ntawm lub cev thiab tshuaj lom neeg **

| Khoom|BPC -157|GHK-CU|TB -500 |

|--------------|------------------|------------------|------------------|

| ** Molecular hnyav **|~ 1419 da|~ 401 da|~ 4963 da |

#### ** {{2.} synergistic Thov cov xwm txheej **

- ** COMMINININININININ DRESS Kev daws **: BPC -157 (angiogenesis) nrawm nrawm tob tob kho mob zoo mob kho mob.

- ** Kev tawm tsam kev laus sib xyaw ua ke **: GHK-CU (collagen reneneration) +}}}} (antioxidant) txhim kho cov tawv nqaij tawv nqaij tag nrho.

- ** Kev ua si kis las rov qab cocktail Kev kho mob Kab mob **: Kev sib xyaw ua ke ntawm peb tus neeg tuaj yeem pab txhawb kev mob leeg cov leeg, txhawb cov kev ua kom ntev thiab txhim kho cov kev ua siab ntev.

#### ** {{3. npaj thiab kev siv ceev faj "

- ** Tb -500 • Pom zoo tias kev siv cov kuab tshuaj uas muaj acetic acid .

- ** Kev Tswj Kev Tswj Xyuas **: Kev txhaj tshuaj lossis kev txhaj tshuaj hauv zos yog lub ntsiab hauv zos, thiab GHK-CU tuaj yeem thov siv sab nraud rau cov tawv nqaij .

- ** DOSAGE MANUCT **: BPC -157 (10 x / {}}}} (10mg / party) {7} {7} {}

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### ** {5. Kev Tshawb Nrhiav Yav Tom Ntej **

- ** Nanocarrier xa khoom **: txhim kho lub transdermal nqus tus nqi ntawm ghok-cu thiab bioavailability ntawm tb-500.

- ** PENE qhia kev tswj hwm kev mechanism **: In-in-tob-157 's cov hom phiaj ntawm qib ecigenetic theem.

- ** Kev tshuaj xyuas kev nyab xeeb kev nyab xeeb **: Kev saib xyuas kev sib raug zoo mus kuaj xyuas cov kev txaus ntshai ntawm kev kho cov tshuaj high-{3}}

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### ** Xaus **

BPC -157, GHK-CU thiab kev ua haujlwm ntawm cov phiaj xwm kev kho mob thiab txhawb nqa kev txhim kho ntawm tus kheej thiab kev txhim kho cov phiaj xwm ntawm tus kheej thiab txhawb nqa cov tshuaj txhim kho thiab kev tshawb nrhiav mechanism, peb lub siab yuav dhau los ua cov khoom tseem ceeb los tawm tsam cov ntaub so ntswg thiab kev laus.