Khoom Taw Qhia
Lub npe:2, 4-} dnp
Cov txiaj ntsig khoom:Kev poob phaus sai yam tsis muaj kev tawm dag zog
CAS:51-28-5
Peev xwm: 200mg * 50 / lub raj mis
Yam khoom:Finished Capsule (BNP)
Txee Lub Neej:2-3Xyoo (Lub hnub ntim khoom yuav muaj yeej)
BNP Hom 2 yog dab tsi, 4-DNP
BNP hom 2,4-Dinitrophenol (2,4-DNP lossis DNP luv luv) yog cov organic compound dav siv hauv kev lag luam thiab tshuaj tshawb fawb, nrog rau cov tshuaj formula C_6H{{5 }}N_2O_5. DNP yog thawj zaug siv los ua cov xim, ntoo preservative thiab tshuaj tua kab nyob rau hauv thaum ntxov xyoo pua 20th, thiab kuj tau siv los ua tshuaj poob phaus. Txawm li cas los xij, vim nws muaj kev cuam tshuam loj heev rau tib neeg lub cev, tam sim no tau txwv nruj nruj los yog txwv tsis pub nyob hauv ntau lub tebchaws.
Lub cev thiab tshuaj muaj zog
1. ** Cov qauv tshuaj thiab cov qauv molecular **:
- Tshuaj formula: C_6H_4N_2O_5
- molecular hnyav: 184.11 g / mol
- 2,4-DNP yog phenol derivative nrog ob pawg nitro (-NO_2) ntawm lub nplhaib benzene thiab muaj zog oxidizing muaj peev xwm.
2. ** Pom zoo **:
- daj lossis txiv kab ntxwv crystalline khoom.
- Yooj yim loj heev nyob rau ntawm qhov kub thiab txias, ua rau muaj kev txob tshuaj.
3. ** Solubility **:
- Cov solubility hauv dej yog tsawg, tab sis nws tuaj yeem yaj hauv cov kuab tshuaj organic xws li ethanol thiab ether.
- Muaj peev xwm tsim cov ntsev, yog li solubility nce nyob rau hauv alkaline tej yam kev mob.
4. ** Melting taw tes thiab boiling taw tes **:
- Melting point: txog 108 degree
- Kub taw tes: kwv yees li 297 degree
- Lub decomposition kub yog tsawg, thiab nws yuav decompose nyob rau hauv high kub los tsim cov pa phem.
5. ** Toxicity **:
- DNP yog tshuaj lom rau tib neeg lub cev, tshwj xeeb tshaj yog ua rau muaj kev puas tsuaj rau lub ntsws, lub siab thiab cov hlab plawv.
- Nws yog ANEABOLIC activator uas tuaj yeem nce lub cev metabolic tus nqi thiab yog li ntawd muaj qhov cuam tshuam kub ntawm lub cev, lub plawv dhia, thiab lwm yam.
Metabolism thiab toxicology
Lub ntsiab muaj nuj nqi ntawm 2, 4- dnp hauv lub cev yog cuam tshuam nrog cov protochondria ntawm mitochondria, yog cuam tshuam nrog cov kev ua pa ua pa ntawm cov hlwb thiab cuam tshuam ntawm ATP ntau lawm. Thaum lub sij hawm metabolic cov txheej txheem, cov hlwb tsis tuaj yeem siv cov piam thaj thiab cov rog ua ke los ua hluav taws xob. Hloov chaw, lawv oxidize thiab decompize cov tshuaj no rau hauv tshav kub, ua rau lub cev lub cev ua kom loj hlob me me, yog li siv cov calories ntau. Txawm li cas los xij, txoj kev no tuaj yeem ua rau muaj kev txawv txav hauv lub cev thiab yog nrog rau ntau yam kev txom nyem.
1. **Half-life**: DNP muaj ib nrab-lub neej nyob rau hauv tib neeg lub cev, feem ntau ntawm 5 mus rau 7 teev.
2. **Excretion**: Feem ntau metabolized los ntawm daim siab thiab tawm hauv cov zis.
3. **Kev mob toxicity**:
- koob tshuaj lom: Nws feem ntau ntseeg tau tias koob tshuaj 50-200 mg yuav ua rau muaj cov tsos mob lom.
- Cov koob tshuaj tuag: Cov koob tshuaj yog kwv yees li 3-4 mg / kg lub cev hnyav. Rau cov neeg laus, ntau tshaj 500 mg yuav ua rau tuag taus.
4. **Kev mob toxicity**: tuaj yeem ua rau xeev siab, ntuav, mob taub hau, tawm hws, plawv dhia, thiab tej zaum yuav ua rau mob plawv.
5. ** Mob toxicity**: Ntev ntev yuav ua rau cov tsos mob xws li daim siab puas, paj hlwb puas, qhov muag tsis pom kev, thiab daj ntawm daim tawv nqaij.
Cov ntawv thov thiab cov kev txwv
1. ** Siv siv **:
- Ua ib qho nruab nrab hauv kev tsim cov xim.
- Siv los ua tshuaj tua kab thiab ntoo preservatives, tab sis tam sim no lawv feem ntau hloov.
2. **Cov tshuaj poob phaus (keeb kwm siv)**:
- Vim tias DNP tuaj yeem ua rau lub cev kub thiab lub zog metabolic, nws tau siv los ua cov tshuaj poob phaus hauv xyoo 1930, tab sis tau maj mam txwv vim muaj kev phiv loj heev.
3. **Lab siv**:
- Hauv cov organic chemistry, DNP tuaj yeem siv rau hauv kev tsom xam ntawm ketones thiab aldehydes ua cov tshuaj reagent kom kuaj pom cov khoom sib xyaw no.
4. ** Kev txwv thiab xiam oob qhab **:
- Vim muaj toxicity siab thiab lethality ntawm DNP, feem ntau lub teb chaws tau cais nws raws li ib tug nruj tswj cov khoom, uas yog txwv rau kev lag luam siv thiab muaj kev tswj nruj heev.
Kev cuam tshuam ib puag ncig
DNP yog tus tsis ruaj khov nyob rau hauv ib puag ncig thiab nyuaj rau degrade. Tom qab nkag mus rau lub cev dej thiab av av, nws yuav ua rau lub cev muaj kab ke thiab ua rau muaj tshuaj lom rau cov tsiaj muaj sia thiab cov kab mob av av. Yog li ntawd, kev siv thiab tuav ntawm DNP yuav tsum tau nruj me ntsis tswj kom tsis txhob nkag mus rau ib puag ncig.
Kev siv tau ntawm 2, 4- dnp
2,4-Dinitrophenol (2,4-DNP) yog ib qho tshuaj lom neeg uas feem ntau siv hauv kev tshawb fawb biochemical hauv chav kuaj, feem ntau yog rau kev kuaj xyuas cov tshuaj reagents. BNP hom 2,4-DNP yog ib lub siab purity 2,4-dinitrophenol reagent. Txawm hais tias 2,4-DNP yog qhov muaj txiaj ntsig zoo rau kev tshawb fawb tshawb fawb nyob rau hauv qee qhov xwm txheej, nws ua rau muaj kev pheej hmoo ntau dua rau tib neeg lub cev, yog li yuav tsum tau saib xyuas tshwj xeeb thaum lub sijhawm sim ua haujlwm. Cov hauv qab no yog cov pej xeem, kev siv, thiab kev ceev faj rau kev siv BNP hom 2,4-DNP.
Muaj feem
BNP Hom 2, {{4- dnp feem ntau haum rau cov kws tshaj lij siv hauv cov teb hauv qab no lossis cov xwm txheej:
1. ** Cov kws tshawb nrhiav biochemical **: hauv kev tshawb fawb biochemical, 2, {{{} DNP tuaj yeem siv tau ua cov khoom siv tshuaj tiv thaiv los saib xyuas cov metabolites thiab enzyme tshua.
2. **Environmental science and toxicology researchers**: Nyob rau hauv ib puag ncig kev tsom xam thiab toxicology tshawb fawb, 2, 4-DNP tuaj yeem siv los ua cov tshuaj tua kab mob los pab txheeb xyuas cov tshuaj lom neeg nyob hauv ib puag ncig.
3. ** Kev tshawb nrhiav kho mob **: 2, {2}} dnp tau siv nyob rau hauv qee cov kev tshawb fawb metabolic, tab sis nws feem ntau nws tsis siv rau kev sim tib neeg.
4. **Organic chemistry laboratory technicians**: 2,4-DNP yog siv rau cov kev ntsuam xyuas cov tshuaj lom neeg cov tshuaj lom neeg, tshwj xeeb tshaj yog rau kev txheeb xyuas cov carbonyl tebchaw xws li aldehydes thiab ketones.
Yuav Siv Li Cas
BNP Hom 2, {4- dnp feem ntau yog muab rau hauv daim ntawv ntawm cov hmoov tawv thiab xav tau kom muaj kev daws teeb meem tsim nyog thaum siv. Txoj kev siv tshwj xeeb yog raws li hauv qab no:
1. **Kev sim ua haujlwm**: Raws li qhov kev xav tau ntawm kev sim, 2, 4-DNP yog tov nrog cov kuab tshuaj tsim nyog (xws li ethanol, methanol, thiab lwm yam) los ua ib qho 0.1 %-1% daws raws li kev tshawb nrhiav reagent.
2. **Sample test**: Cov qauv yuav tsum tau sim yog tov nrog 2, 4-DNP tov thiab reacted tag nrho. Feem ntau muaj daj lossis txiv kab ntxwv precipitate yog generated. Cov tshuaj tiv thaiv no tuaj yeem siv los txheeb xyuas cov ntsiab lus carbonyl.
3. **Quantitative detection**: Hauv cov kev sim tshwj xeeb, spectroscopy tuaj yeem siv los txiav txim siab qhov concentration ntawm cov khoom siv tshuaj tiv thaiv thiab nkag siab txog qib ntawm cov tshuaj tiv thaiv kom ua tiav lub hom phiaj ntawm kev soj ntsuam ntau.
Kev ceev faj rau kev siv
2.
1. ** Siv cov hnab looj tes tiv thaiv hnab looj tes 2, {} DNP, hnav cov khaub ncaws tiv thaiv uas tsim nyog rau kev sib cuag nrog tawv nqaij thiab qhov muag.
2. **Qhov chaw ua haujlwm**: Ua haujlwm hauv lub fume hood kom tsis txhob nqus plua plav lossis vapor. Ib puag ncig qhov cua pab txo qhov kev pheej hmoo ntawm kev nqus pa ntawm cov pa thiab plua plav.
3. "Zam kev sib cuag **: Zam kev sib chwv tawv nqaij, nqus tau. Yog tias muaj kev tiv tauj yuam kev ua, yaug tam sim ntawd nrog dej ntau thiab nrhiav kev kho mob sai li sai tau.
4. ** Cia **: BNP Hom 2, {2}} dnp yuav tsum muab ntim rau hauv ib lub taub hau qhuav, kom deb ntawm lub hnub ci thiab kub kom tiv thaiv kev lom zem.
Pov tseg kom nyab xeeb
Thaum tshem tawm cov khib nyiab, 2, 4- Dnp yuav tsum tau saib xyuas kom tsis txhob raug tshem tawm ncaj qha rau hauv lub lim dej lossis hu rau ib puag ncig. Siv cov kev daws teeb meem thiab cov tshuaj ntsuam yuav tsum muab pov tseg los ntawm cov tuam txhab kev khib nyiab kom tsis txhob muaj kuab paug ib puag ncig.
Lwm Yam Kev Ceev Dua
Kev siv ntawm 2, {4- dnp yuav tsum tau nqa tawm hauv nruj kev cai nrog kev tswj tshuaj lom neeg. Cov neeg ua hauj lwm hauv kev kuaj cov neeg ua haujlwm uas xav tau siv lub reagent no ntev, kuaj xyuas kev noj qab haus huv ib txwm ua raws li kev sim ib puag ncig. Ib qho ntxiv, cov neeg ua haujlwm tsis muaj kev cob qhia ua haujlwm yuav tsum zam kom tsis txhob ua haujlwm xws li reagents los tiv thaiv kev huam yuaj.
BNP Hom 2, 4- DNP Lub Luag Haujlwm
BNP hom 2,4-DNP (2,4-dinitrophenol) yog ib qho tshuaj uas tau siv rau hauv kev poob phaus, tab sis nws siv yog qhov txaus ntshai heev. Nws yog qhov pab tau kom nkag siab txog cov txiaj ntsig thiab cov txheej txheem ntawm kev txiav txim ntawm DNP, tab sis thov nco ntsoov tias nws cov txiaj ntsig kev noj qab haus huv tsis zoo yog qhov hnyav heev uas nws siv tau txwv hauv ntau lub tebchaws.
1. Cov roj sai sai hlawv cov nyhuv
- Lub luag haujlwm tseem ceeb ntawm 2,4-DNP yog txhawm rau txhawb kev rog rog los ntawm kev ua kom cov metabolism sai. Nws ua rau cov hlwb tawg qee qhov cua sov thaum tsim lub zog (ATP), yog li hlawv lub cev rog los ntawm kev siv lub zog ntau dua.
- Ntawm cov koob tshuaj uas tsim nyog, DNP tuaj yeem ua rau nce qib ntawm cov metabolism hauv basal (BMR), ua rau tib neeg mus txuas ntxiv hlawv calorie ntau ntau txawm tias tsis muaj kev tawm dag zog.
2. Inhibit rog cia
- DNP txo cov roj cia los ntawm kev ua kom cov roj metabolism sai. Nws tso cai rau cov hlwb los hloov lub zog ntau dua rau hauv cov cua sov (tsim cov nyhuv thermal), yog li txo cov nqi zog uas khaws cia ua rog.
3. Ua kom lub cev kub (thermogenesis)
- Noj DNP tuaj yeem ua rau lub cev kub nce me ntsis vim tias nws ua rau kom kub poob los ntawm inhibiting ATP synthesis. Txawm hais tias qhov no tuaj yeem ua rau tsis xis nyob, nws kuj yog ib feem ntawm kev poob phaus ntawm DNP vim tias calories tau poob rau hauv txoj kev no.
4. Kev poob phaus sai sai
- DNP yog lub npe hu ua txoj hauv kev sai thiab muaj txiaj ntsig zoo rau kev poob phaus, tshwj xeeb tshaj yog tsim rau cov neeg uas xav kom poob rog sai sai hauv lub sijhawm luv. Txawm li cas los xij, txoj kev no tsis haum rau txhua tus neeg vim muaj teeb meem kev nyab xeeb.
5. Kev rog tsis tau tso siab rau kev tawm dag zog
- Vim hais tias DNP nws tus kheej nce metabolism nce thiab cov neeg muaj nqi caloric, cov neeg siv tuaj yeem txo cov rog ntawm lub cev kom muaj ntau yam txawm tias tsawg ntawm cov haujlwm. Cov yeeb yam no tau nyiam qee tus neeg nrhiav "tsis yog kev tawm dag zog poob phaus" rau qee yam.
Ceeb Toom Txog Kev Nyab Xeeb Kev Nyab Xeeb
Txawm hais tias DNP muaj cov teebmeem poob phaus tseem ceeb, nws cov kev mob tshwm sim muaj mob loj thiab tseem yuav ua rau neeg tuag taus. DNP tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:
- ** CYPERthermia **: DNP tuaj yeem ua rau lub cev kub kom sawv, uas yuav ua rau kub taub hau lossis ua rau muaj kev kub ntxhov hauv cov mob hnyav.
- ** SEPHYTHMIA **: Kev siv ntau dhau tuaj yeem ua rau muaj teeb meem plawv kev xws li lub plawv dhia tsis xwm yeem thiab kev kub ntxhov.
- ** Cov tshuaj tiv thaiv tsis haum **: Qee cov neeg muaj kev nkag siab zoo rau DNP, uas yuav ua rau pob khaus, khaus, thiab txawm tias anaphylactic shock.
- ** Siv kev puas tsuaj hauv DNP yuav ua rau lub siab puas yuav ua rau lub siab, raum puas thiab lwm cov plab hnyuv siab raum, ua rau muaj kev puas tsuaj.
Vim tias qhov kev pheej hmoo ntawm DNP yog qhov siab heev thiab tsis tuaj yeem kwv yees, cov neeg kho mob feem ntau tawm tswv yim tawm tsam kev siv nws rau kev poob phaus. Txawm hais tias muaj cov nyhuv luv luv luv, cov kev mob tshwm sim muaj peev xwm ua rau nws muaj txiaj ntsig ntau dua qhov nce.
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FAQ
Q: 2 {4- dnp? Dab tsi yog nws cov tshuaj lom neeg?
A: 2, {{4- dinitropenol (abinned Nws cov mis nyuj yog c {4}} h _4 n {} _5. Nws muaj cov tsos ntawm daj muaju, iab iab, yog insoluble hauv dej tab sis soluble hauv cov kuab tshuaj organic, thiab muaj qee yam volatility thiab toxicity. 2, {{9 {9}} dnp yog cov oxidant muaj zog, thiab nkag siab txog kev sib txhuam siab thiab kev sib txhuam, yog li kev saib xyuas kom tau them rau nws cov chaw cia khoom thiab siv.
Q: Cov yam ntxwv ntawm BNP hom 2 yog dab tsi, 4-DNP?
A: BNP hom 2,4-DNP yog ib qho kev lag luam thiab kev sim tshuaj uas paub txog nws cov purity siab thiab kev tswj xyuas nruj, ua kom muaj kev ua haujlwm siab thiab ruaj khov hauv cov txheej txheem tshuaj tiv thaiv thiab cov ntawv thov kev lag luam. BNP hom feem ntau muab 2,4-DNP ntawm cov qib purity sib txawv kom tau raws li cov kev xav tau sib txawv los ntawm kev soj ntsuam tshuaj mus rau kev tsim khoom thiab kev ua haujlwm.
Q: Cov ntawv thov cov npe ntawm BNP Hom 2, 4- dnp?
A: Cov ntawv thov tseem ceeb ntawm BNP hom 2,4-DNP suav nrog cov hauv qab no:
- ** Tshuaj ntsuam xyuas**: Hauv cov chemistry organic, 2, 4-DNP feem ntau yog siv rau kev soj ntsuam zoo ntawm aldehydes thiab ketones. Cov xim daj rau txiv kab ntxwv-liab precipitate uas ua los ntawm cov tshuaj tiv thaiv nrog cov tshuaj no tuaj yeem siv los txheeb xyuas cov pa roj carbon monoxide.
- **Organic synthesis**: Raws li qhov nruab nrab, 2, 4-DNP plays lub luag haujlwm catalytic lossis cov tshuaj tiv thaiv-txhim kho cov organic synthesis hauv thaj chaw dyes, explosives, thiab lwm yam.
- ** Kev ua liaj ua teb **: Nws tau siv los ua tshuaj tua kab thiab tshuaj tua kab yav dhau los, tab sis nws daim ntawv thov hauv cheeb tsam no maj mam txo qis vim nws cov tshuaj lom ntau.
Q: Kuv yuav ua li cas tau mloog thaum siv BNP hom 2, 4- dnp?
A: Vim tias 2, {4- dnp yog ib hom tshuaj muaj kev phom sij, BNP Hom 2, {} Dnp xav tau kev saib xyuas tshwj xeeb thaum siv:
- ** Kev tiv thaiv kev tiv thaiv **: hnab looj tes, hnab looj tes, thiab kev ua haujlwm yuav tsum hnav thaum siv cov tawv nqaij kom tsis txhob muaj plua plav lossis nqus plua plav.
- ** Cia cov kev cia kom zoo ** **: 2, {2}} Dnp yuav tsum muab cia rau hauv qhov chaw txias, kom qhuav, chaw sov thiab muaj zog oxidants.
- ** Pov Tseg Pov Tseg **: Vim tias 2 {{{2} Yuav tsum tau muab cov kev tswj hwm tshuaj lom neeg thiab tsis txhob raug rho tawm ncaj qha rau hauv dej phwj lossis ib puag ncig.
Q: Yuav ua li cas ua cov kev ntsuas zoo ntawm BNP Hom 2, {1}}}} dnp nrog aldehydes thiab ketones?
A: 2; Txij li thaum dinitrophenylhydrazone tsim los ntawm txhua qhov sib txawv aldehyde lossis ketone muaj qhov tshwj xeeb melting point, txawv aldehydes lossis ketones tuaj yeem txheeb xyuas los ntawm kev ntsuas qhov melting point ntawm precipitate. Cov txheej txheem tshuaj tiv thaiv no yog siv dav hauv kev tshuaj ntsuam xyuas cov organic thiab yog ib txoj hauv kev los txheeb xyuas cov pa roj carbon monoxide.
Cim npe nrov: BNP 2, {4- dnp 200mg CAS: {} {} {{{{} Cov neeg tsim khoom, cov chaw tsim khoom, Hoobkas
