Hwm High{0}}purity Peptides SS-31

1. Basic Overview and Classification of SS-31

Los ntawm kev pom kev ua haujlwm ntawm kev faib tawm, SS-31 belongs rau mitochondrial tiv thaiv peptide / mitochondrial functional regulatory peptide qeb.

Los ntawm cov qauv kev xav, nws yog nyob rau hauv luv luv - chainsynthetic polypeptide qeb.

Los ntawm qhov kev xav ntawm daim ntawv thov, nws yog feem ntau cais raws li kev tshawb fawb -qib thiab siab -kawg roj ntsha ua haujlwm peptide raw khoom.

SS-31 muaj qhov luv luv amino acid ib ntus tab sis muaj qhov tshwj xeeb spatial conformation, ua kom nws ncaj qha mus nrhiav thiab khi rau cardiolipin ntawm sab hauv mitochondrial membrane. Qhov kev muaj peev xwm ntawm lub hom phiaj no muab nws qhov kev lees paub siab heev thiab kev tshawb fawb tus nqi ntawm cov polypeptides zoo sib xws.

2. Cov txiaj ntsig tseem ceeb thiab cov yam ntxwv ntawm SS-31

Muaj zog Mitochondrial Targeting

SS-31 qhov txiaj ntsig zoo tshaj plaws nyob hauv nws qhov kev xaiv siab. Nws tuaj yeem nkag mus rau sab hauv mitochondrial daim nyias nyias cheeb tsam yam tsis muaj kev vam khom lub peev xwm ntawm daim nyias nyias thiab tsim kev ruaj ntseg nrog cardiolipin, yog li txhim kho cov qauv kev ruaj ntseg ntawm mitochondrial membrane.

Tsis zoo li qee qhov activating lossis inhibiting peptides, SS-31 tsis ncaj qha cuam tshuam nrog kev hloov pauv ntawm cov teeb liab nuclear lossis cov kab ke hormonal. Hloov chaw, nws ua haujlwm ntawm qhov chaw ntawm lub zog metabolism, ua rau nws yog "kev ua haujlwm zoo tshaj plaws" peptide.

Nws muab cov teebmeem antioxidant nrog kev txhim kho lub zog. SS-31 txo qis kev tsim cov pa oxygen ntau dhau (ROS) hauv mitochondria thaum nce ATP synthesis efficiency, ua rau nws muaj nuj nqis heev hauv kev tiv thaiv kev laus, kev tiv thaiv cov ntaub so ntswg, thiab kev kawm ntev.

Nws exhibits siab stability thiab reproducibility. Raws li ib tug synthetically tsim peptide luv luv, SS-31 qhia tau hais tias zoo batch- mus rau -batch stability, ib tug zoo-txhais qauv, thiab pab txhawb kev tswj kom zoo thiab rov tsim dua thwmsim.

3. Physicochemical Performance Analysis

SS-31 yog ib qho hluavtaws peptide compound, feem ntau uas twb muaj lawm raws li lyophilized hmoov. Nws lub ntsiab physicochemical zog muaj xws li:

Molecular Hom: Linear luv peptide

Molecular Luj: Kwv yees li 639 Da (qhov txawv me ntsis nyob ntawm daim ntawv ntsev)

Solubility:

- Yooj yim soluble hauv dej deionized

- Soluble nyob rau hauv weakly acidic buffer daws

- Zoo solubility nyob rau hauv nruab nrab los yog me ntsis alkaline tej yam kev mob

Hais txog kev ruaj ntseg, SS-31 qhia txog kev ruaj ntseg tshuaj zoo nyob rau hauv qis kub, qhuav, thiab lub teeb- tiv thaiv tej yam kev mob. Hauv daim ntawv daws teeb meem, qhov qis- qhov kub thiab txias tau raug pom zoo, zam kom tsis txhob rov ua kom khov-thaw lub voj voog kom tswj tau nws cov qauv kev ntseeg siab thiab kev ua haujlwm lom neeg.

4. Xim, tsos, thiab cov yam ntxwv ntawm kev xav

Siab -cov ntaub ntawv zoo SS-31 feem ntau pom cov yam ntxwv hauv qab no:

Xim:

- Dawb dawb los yog tawm -dawb

- Tsis muaj qhov pom tseeb tsis muaj xim lossis qhov chaw

Daim ntawv:

- Cov hmoov zoo lyophilized

- Uniform kev ntxhib los mos thiab zoo flowability

Tsis hnov ​​tsw:

- Zoo li ntxhiab tsw

- Yuav tsum tsis txhob muaj qhov khaus khaus lossis txawv txav

Yog tias cov khoom siv raw pom pom tseeb yellowing, clumping, lossis dampness, nws feem ntau cuam tshuam nrog kev cia khoom tsis raug lossis tsis txaus purity.

5. Cov txheej txheem ntau lawm thiab Purity Control

SS-31 feem ntau yog npaj siv **khoom-theem peptide synthesis thev naus laus zis (SPPS)**, ua kom tiav cov txheej txheem tag nrho los ntawm kev sib xyaw ua ke ntawm cov amino acid residues. Tom qab ntawd nws yog purified los ntawm pyrolysis, crude purification, thiab high-performance kua chromatography (HPLC).

Cov ntsuas qhov tseem ceeb rau siab -zoo SS-31 suav nrog:

- Purity feem ntau ntau dua lossis sib npaug li 98%

- Ib lub ntsiab lus meej meej nrog kev tswj xyuas nruj ntawm impurity peaks

- Molecular hnyav raws li tau lees paub los ntawm huab hwm coj spectrometry

- Cov ntsiab lus noo noo thiab cov kuab tshuaj residual ua tau raws li cov qauv

Cov ntsuas no ncaj qha txiav txim siab nws txoj kev ntseeg siab hauv kev tshawb fawb txog kev tshawb fawb thiab kev siv siab - kawg.

6. Cov lus qhia thiab kev tshawb fawb tus nqi

Mitochondrial Function Research: SS-31 feem ntau yog siv los kawm mitochondrial membrane stability, electron thauj saw efficiency, thiab lub zog metabolism tsis zoo qauv.

Kev Tiv Thaiv -Kev laus thiab Kev Tiv Thaiv Cell: SS-31 tau siv dav los ua kev tswj hwm lossis kev cuam tshuam hauv cov qauv ntawm cellular aging, cov ntaub so ntswg puas, thiab oxidative stress.

Myocardial, Nervous, thiab Muscle Kev Tshawb Fawb: Vim muaj kev vam khom siab ntawm siab -zog- xav tau cov ntaub so ntswg ntawm mitochondria, SS-31 tau nyiam cov kev tshawb fawb tseem ceeb hauv cov cheeb tsam.

Kev Tshawb Fawb Cov Khoom Siv Raw Khoom: Hauv kev tshawb fawb tshawb fawb thiab kev sim ua haujlwm, SS-31 suav tias yog peptide muaj txiaj ntsig zoo rau kev ua kom zoo ntawm mitochondrial muaj nuj nqi.

7. Cov lus pom zoo khaws cia thiab thauj mus los

Txhawm rau kom ntseeg tau qhov zoo ntawm SS-31, cov hauv qab no yuav tsum ua raws li:

- Lub xeev Undissolved: Khaws ntawm qhov kub thiab txias (2–8 degree), nyob rau hauv qhuav, lub teeb - tiv thaiv, thiab ntim ntim.

- Kev daws teeb meem: Pom zoo rau luv luv - siv sijhawm; khaws cia ntawm qhov kub thiab txias thiab tsis txhob rov khov dua -thaw cycles.

- Thaum lub sij hawm thauj mus los: Tiv thaiv los ntawm noo noo, kub siab, thiab ncaj qha tshav ntuj.

8. Kev ntsuam xyuas dav dav thiab cov ntsiab lus

SS-31, raws li ib txwm mitochondrial- tsom rau kev ua haujlwm peptide, muaj qhov chaw sib txawv hauv tsev neeg peptide. Nws tsis tso siab rau cov tshuaj hormones ib txwm muaj tab sis txhim kho kev ua haujlwm ntawm lub zog hluav taws xob ntawm lub zog hluav taws xob, tus yam ntxwv uas ua rau nws ntev -lub sij hawm tus nqi hauv kev tshawb fawb thiab kev siv high-end.

Los ntawm cov tsos zoo, physicochemical zog, kev ruaj ntseg rau kev ua haujlwm muaj peev xwm, siab -zoo SS-31 nthuav tawm siab sib xws thiab tswj tau. Rau cov kws tshawb fawb tsom mus rau mitochondrial noj qab haus huv, lub zog metabolism, thiab optimization ntawm lub hauv paus cellular zog, SS-31 yog ib tug sawv cev high-end functional peptide raw khoom.

Txhawb txoj kev them nyiaj

 

 

Peb txhawb ntau txoj kev them nyiaj

 

Tiv tauj peb

 

 

Koj tuaj yeem tiv tauj peb ntawm WhatsApp, Telegram, Gmail, Proton Mail, thiab lwm yam.

Hu rau peb tam sim no Los ntawm Email

Cim npe nrov: hwm siab -purity peptides ss-31, Tuam Tshoj hwm high-purity peptides ss-31 manufacturers, lwm tus neeg, Hoobkas