Hepius salbutamol 20mg CAS: 18559-94-9

**Salbutamol** yog ib qho ua rau luv luv 2-adrenergic receptor agonist (SABA) siv los kho cov kab mob ua pa, tshwj xeeb tshaj yog mob hawb pob thiab mob ntsws ntsws ntev (COPD). HEPIUS yog ib qho ntawm nws cov chaw tsim khoom lossis cov khoom lag luam. Cov hauv qab no yog cov lus qhia ntxaws ntxaws rau Salbutamol, suav nrog cov ntaub ntawv xws li lub cev thiab tshuaj lom neeg, ntau npaum li cas, ib nrab-lub neej thiab lub voj voog tshuaj.

### ** 1. Tshuaj thiab lub cev muaj zog **

- **} {1}} ({2}} hydroxy}}} (tert-butylamino) etylamol

Cov mis mos molecular: C13H21NO3

- Molecular Luj: 239.31 g / mol

- ** Pom zoo **: Feem ntau dawb crystalline hmoov, soluble hauv dej.

- ** Solubility **:

- Yooj yim soluble hauv dej

- soluble hauv ethanol

- Tsis zoo soluble nyob rau hauv tsis-polar kuab tshuaj

- ** PKA tus nqi **: 9.3 (Pab Pawg Phenolic)

### ** 2. Pharmacological A Siab **

Salbutamol ua rau kev so ntawm bronchial du cov leeg los ntawm kev ua kom {{0} {adrenergic recors, yog li hloov urrengoring bronchospasm, txhim kho cov pa hawb pob, thiab cov tsos mob hawb pob thiab cov tub ceev xwm. Nws kuj tseem siv tau los tiv thaiv kev tawm dag zog ua kev tawm tsam bronchospasm.

### ** 3. Muab thiab kev tswj hwm **

- ** Inhalation form (common)**:

- Cov neeg laus thiab cov menyuam muaj 12 xyoos dhau los: feem ntau {2}} micrograms ({} puffs) txhua lub sijhawm, ib zaug txhua {teev.

- Cov menyuam {6-12}} xyoo: 100 micrograms txhua lub sijhawm, ib zaug txhua {}} teev.

- **Qhov ncauj daim ntawv** (cov ntsiav tshuaj/syrup):

- Cov neeg laus: {{2-4 mg, 3-4 sij hawm ib hnub.

- Cov menyuam: Kho cov tshuaj raws li lub cev hnyav, feem ntau 0. {}}. 2 mg / kg.

- ** Kev txhaj tshuaj txhaj tshuaj ** (tsis tshua siv): suav raws li lub cev hnyav, cov koob tshuaj raug kho los ntawm tus kws kho mob ntawm tus kheej.

** Ceeb Toom **: Kev nqus pa yog txoj kev pom zoo ntawm kev tswj hwm vim tias cov tshuaj ua ncaj qha rau ntawm txoj hlab pa thiab muaj kev phiv tsawg dua.

### 4. Pharmacokinetics **

- ** Absorption **: Kev nqus sai sai tom qab nqus tau cov tshuaj, nrog rau qhov pom tseeb hauv zos.

- ** Bioavailaby **:

- Inhalation: Tsawg bioavailability, tsuas yog 10% -20% absorbed systemically.

- Qhov ncauj: Bioavailability yog li 50%.

- ** Metabolism "feem ntau yog metabolized nyob rau hauv daim siab los ua cov kua nqaij flucuronic acid conjugates.

- ** Ib nrab neej (T1/2)**:

- Kev nqus pa: 3-6 teev.

- Qhov ncauj: 4-6} teev.

- ** Excretion **: Feem ntau tawm los ntawm cov zis, ib qho me me yog tawm nrog cov quav.

### 5. Duration ntawm Effect **

- **Inhalation**: Cov nyhuv kav ntev li ntawm 4-6 teev.

- ** Daim foos Qhov ncauj ntawm ncauj **: Cov nyhuv kav {1}}} sijhawm.

- ** QIBRANENENSUS **: Cov nyhuv ceev, tab sis lub sijhawm luv luv, feem ntau siv rau kev kho mob xwm txheej ceev.

### ** 6. Kev voj voog thiab taw qhia **

Salbutamol tsis xav tau lub voj voog nruj thiab feem ntau yog siv los ntawm kev thov:

- ** Subute Hawbma **: Kev tiv thaiv luv luv ntawm cov tsos mob.

- ** ** Cov mob ntsws asthma thiab CopD tau siv los ua ib feem ntawm txoj kev npaj kho mob ntev, tab sis yuav tsum tau siv ua ke nrog lwm cov tshuaj (xws li nqus tau corticosteroids).

- **Kev tawm dag zog ua rau mob hawb pob**: Siv 15-30 feeb ua ntej kev tawm dag zog.

### ** 7. Cov kev mob tshwm sim ib txwm **

Txawm hais tias Salbutamol muaj txiaj ntsig zoo, nws tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:

- Tes tshee

- Palpitations lossis nce lub plawv dhia

- Mob taub hau

- Hypokalemia (tsis tshua muaj)

- Mob plab hnyuv

Cov kev mob tshwm sim no feem ntau muaj feem ntsig txog kev cuam tshuam, thiab kev pheej hmoo yog qis tshaj nrog cov ntawv nqus dej.

### 8. Contraindications thiab ceev faj **

** Contraindications **:

- Cov neeg uas ua xua rau Salbutamol lossis nws cov khoom xyaw.

- Cov neeg uas muaj ntshav siab hnyav lossis arrhythmia.

- **Cov kev ceev faj**:

- Kev siv mus sij hawm ntev yuav ua rau txo qis kev ua tau zoo (siab ntev).

- Cov neeg muaj kab mob plawv yuav tsum siv ceev faj.

- Cev xeeb tub thiab lactation: Siv raws li kev qhia ntawm tus kws kho mob.

* ### ** cov pej xeem muaj feem xyuam **

Salbutamol yog ib qho kev xaiv ₂-receptor agonist, feem ntau yog siv los txo lossis tiv thaiv cov tsos mob bronchospasm cuam tshuam nrog cov kab mob hauv qab no:

1. ** Tus neeg mob tus neeg mob tus mob hawb pob lossis tiv thaiv kev tawm dag zog ua kev tawm dag zog.

2. ** Tus kab mob ntsws sib deev

3. ** Kev tawm dag zog-ua rau cov neeg mob hawb pob **: siv ua ntej kev tawm dag zog tiv thaiv kev tawm dag zog ua kom muaj mob hawb pob.

#### ** Ua haujlwm tus qauv **

Salbutamol yog ib tug luv luv-acting ₂-receptor agonist (SABA), thiab nws lub ntsiab mechanism ntawm kev txiav txim yog raws li nram no:

1. ** Xaiv cov neeg hauv cov pa hluav taws xob ₂-adrenergic recenors hauv cov hlab pa lub hlwb, ua rau cov leeg leeg ua kom txaus thiab tshem tawm cov pa roj hmab spasm.

2. ** Kev ua kom zoo nkauj rau lub ntsej muag **: Cov tshuaj dilates cov hlab pa, txhim kho airflow, thiab relieves dyspnea.

3. **Inhibit the release of inflammatory factors**: Inhibit mast cells from release inflammatory mediators (xws li histamine) rau qee qhov, thiab txo cov kev tsis haum tshuaj.

#### **Kev siv thiab noj**

Salbutamol muaj nyob rau hauv cov tshuaj rau hauv cov pa, tshuaj noj, thiab txhaj tshuaj. Cov tshuaj hauv qab no feem ntau ua rau muaj kev ua piv txwv los qhia nws cov kev siv thiab kev siv tshuaj ntau:

1. "Cov pa taws ** (AEROSOL lossis cov hmoov qhuav qhuav):

- ** Cov neeg laus thiab cov hluas dua 12 xyoos **: {{2} {{{{{{{{{{{{{{{{{{{{{{{{{{{{{{{{{}

- ** Cov menyuam hnub nyoog 6 txog 12 xyoos **: 100 micrograms (1 tsuag) txhua lub sijhawm, uas tuaj yeem tau txais los ntawm tus kws kho mob.

- **Kev tiv thaiv kev tawm dag zog vim mob hawb pob**: Siv 10-15 feeb ua ntej kev tawm dag zog, 100-200 micrograms txhua zaus.

2. ** Cov ntsiav tshuaj ntawm qhov ncauj lossis kua txiv plig **:

- **Cov neeg laus**: 2-4 mg txhua zaus, 3-4 zaug ib hnub.

- ** Cov menyuam **: Hloov cov koob tshuaj raws li lub cev hnyav, feem ntau 0. 1 mg rau ib kg ntawm lub cev hnyav, 3 zaug ib hnub.

3. **Kev txhaj tshuaj** (rau kev siv tsev kho mob nkaus xwb): Nws yog qhov tsim nyog rau kev mob hawb pob hnyav thiab raug tswj hwm los ntawm cov neeg ua haujlwm kho mob los ntawm kev txhaj tshuaj intravenous lossis subcutaneous.

#### **Cov kev ceev faj**

1. ** Kev phiv zoo **: Cov kev mob tshwm sim muaj xws li palppitations, tes tshee, taub hau, qhov ncauj qhuav, thiab lwm yam .; Thaum muaj mob hnyav, nws yuav ua rau muaj kev fab tshuaj tsis haum lossis kev ua xua.

2. ** Multaindications **: Nws yog contraindicated rau cov neeg uas ua xua rau salbutamol lossis nws cov khoom xyaw.

3. ** Cov neeg muaj cov neeg muaj menyuam yaus, cov poj niam cev xeeb tub, cov neeg mob pub mis niam mis rau cov kab mob plawv yuav tsum siv nws kom ceev faj raws li kws kho mob.

4. ** Kev siv ntau zaus **: Zam kev zam dhau. Yog tias cov tsos mob pheej ua kom loj hlob, nrhiav kev kho mob kom raws sijhawm.

Salbutamol yog cov tshuaj cawm siav thiab tsis tuaj yeem hloov cov tshuaj kho mob mus ntev (xws li nqus tau corticosteroids). Cov neeg siv yuav tsum siv nws raws li qhov xav tau raws li tus kws kho mob cov lus qhia kom tsis txhob siv tshuaj ntau dhau lossis siv tsis raug.

Hepius hom salbutamol (salbutamol) yog ib qho kev ua haujlwm luv 2 yog ib txwm siv los kho tus mob ntsws ua pa xws li tus kab mob ntsws (Coptern). Hepius hom salbutamol muaj qee qhov tseem ceeb hauv kev ua lag luam. Cov hauv qab no yog cov lus qhia ntxaws ntxaws rau nws cov yam ntxwv thiab cov txiaj ntsig los ntawm ntau yam:

### ** 1. Tshuaj zoo thiab ua tau zoo**

1. **High-purity raw cov ntaub ntawv**: HEPIUS hom Salbutamol siv cov ntaub ntawv zoo zoo los xyuas kom meej cov tshuaj purity siab thiab tsis tshua muaj kev phiv.

2. ** Kev ua haujlwm ruaj khov **: Tom qab kho kom nruj kev soj ntsuam cov ntaub ntawv tseeb, hepius cov salbutamol tuaj yeem hloov kho cov leeg pob txha thiab txhim kho dyspnea. Nws txoj kev ua tau zoo yog ruaj khov thiab ntev-ntev, muab cov neeg mob uas muaj kev tiv thaiv kev tiv thaiv kev tiv thaiv.

3. ** Tshaj tawm nrawm dua **: salbutamol yog ib qho luv-ua yeeb yaj kiab 2 tus neeg sawv cev. Hepius txoj kev ua kom zoo rau nws feem ntau siv tau nyob rau hauv feeb tom qab nqus tau sai sai rau kev tawm tsam sai ntawm mob hawb pob lossis bronchospasm.

### ** 2. Kev tsim kho tshiab thiab thev naus laus zis zoo **

1. "Cov Ntawv Dosage Dosage **: Hepius muaj ntau cov ntaub qhwv tshuaj, nrog rau cov pa nqus (MDI, DPI thiab cov ncauj tshuaj kom tau raws li cov neeg mob sib txawv:

- ** TSO CAI RAU LUB LUNGS, nrog rau cov kev mob tshwm sim tsawg dua, tshwj xeeb tshaj yog haum rau cov neeg mob hawb pob thiab Copd.

- ** Npaj qhov ncauj **: Haum rau qee tus neeg mob uas tsis tuaj yeem siv tshuaj rau hauv cov pa tuag, xws li cov neeg laus lossis menyuam yaus.

2. **Kev tswj hwm koob tshuaj meej**: HEPIUS hom siv cov tshuaj tua kab mob siab heev tsim hauv cov khoom nqus nqus pa, uas tuaj yeem ua kom pom tseeb ntawm cov tshuaj ntxiv thiab pab cov neeg mob tswj cov tshuaj zoo dua.

3. **Microparticle technology**: HEPIUS's inhalers siv ultrafine particle technology, uas tso cai rau cov tshuaj kom zoo dua tso rau hauv lub ntsws, txhim kho kev ua tau zoo thiab txo cov khoom pov tseg.

### ** 3. Kev Nyab Xeeb thiab Ua Kom Tau **

1. **Kev tswj cov kev mob tshwm sim**: Los ntawm kev ua kom zoo ntawm cov mis thiab cov txheej txheem, HEPIUS hom Salbutamol txo qis qhov tshwm sim ntawm cov kev mob tshwm sim (xws li palpitations, tes tshee, thiab lwm yam).

2. * Haum rau cov pab pawg sib txawv **: Hepius cov salbutamol tau dhau los ua kom zoo thiab kev nyab xeeb rau menyuam yaus, thiab cov neeg mob uas muaj kev puas tsuaj rau lub siab.

### 4. Kev yooj yim ntawm kev siv **

1. **Humanized inhaler design**: HEPIUS's inhaler adopts lub teeb yuag thiab yooj yim-rau-siv inhaler tsim, uas yog me me thiab portable thiab haum rau siv txhua lub sij hawm thiab nyob qhov twg.

2. **Kev ua haujlwm yooj yim**: Lub tshuab nqus tsev nqus tau yooj yim rau tus tswv thiab haum rau txhua hom neeg mob, txawm tias cov neeg siv thawj zaug tuaj yeem kawm tau yooj yim.

3. ** Kev ruaj ntseg ntev ntev **: HEPIUS's Salbutamol cov khoom muaj lub neej txee ntev thiab tuaj yeem tswj tau qhov ua tau zoo nyob rau hauv qhov sib txawv ntawm qhov kub thiab txias.

### ** 5. Hom Tshuaj Rov Qab thiab Kev Pab **

1. **R&D thiab ntau lawm lub zog**: HEPIUS muaj kev nplua nuj thiab muaj zog R&D muaj zog hauv kev lag luam tshuaj. Kev tsim cov khoom nruj me ntsis ua raws li cov qauv thoob ntiaj teb GMP los xyuas kom meej qhov zoo thiab sib xws ntawm txhua pawg tshuaj.

2. ** Daim ntawv pov thawj thoob ntiaj teb **: HEPIUS's Salbutamol tau dhau daim ntawv pov thawj ntawm ntau lub teb chaws cov cai tswj hwm tshuaj, suav nrog FDA, EMA, WHO, thiab lwm yam, thiab nws cov khoom zoo tau raug lees paub thoob ntiaj teb.

3. **Txoj kev txhawb nqa neeg mob ua tiav**: HEPIUS muab kev qhia ntawv thiab kev txhawb nqa rau tus neeg mob, suav nrog kev qhia txog tshuaj, kev pabcuam tom qab thiab kev sib tham txog kev noj qab haus huv, los pab cov neeg mob txhim kho kev kho mob thiab kev ua neej zoo.

### ** 6. Kev lag luam thiab kev nkag tau **

1. ** Tus nqi tsim nyog **: Thaum ua kom zoo, HEPIUS hom muab cov nqi sib tw, tso cai rau cov neeg mob ntau dua los them cov nqi kho mob.

2. **Txoj kev lag luam dav dav**: HEPIUS's Salbutamol faib network npog ntau lub teb chaws thiab cheeb tsam thoob ntiaj teb, kom ntseeg tau tias cov tshuaj siv tau yooj yim.

### ** 7. Kev tiv thaiv ib puag ncig thiab kev sib raug zoo **

1. ** Ib puag ncig cov txheej txheem tsim khoom ib puag ncig **: Hepius tau cog lus rau cov chaw tsim khoom ntsuab, thiab cov kauj ruam ntau ntxiv tau ua rau cov pa roj carbon monissions.

2. ** Cov phiaj xwm kev noj qab haujlwm rau pej xeem **: Cov phiaj xwm kev kawm rau cov pej xeem muaj feem cuam tshuam nrog kev ua pa rau kev ua pa rau kev ua pa rau kev sib raug zoo.

### ** Ntsiab Lus **

Hepius Hom salbutamol tau dhau los ua qhov kev xaiv ntau yam rau ntau cov mob hawb pob thiab cov tub ceev xwm vim nws cov khoom lag luam siab zoo, tsim kev nyab xeeb, kev nyab xeeb thev naus laus zis, kev nyab xeeb thiab tib neeg tsim. Seb puas muaj kev pab nrawm nrawm lossis kev tswj hwm kev ua haujlwm ntev, hepius salbutamol tau yeej kev ntseeg siab ntawm cov neeg mob thiab cov kws kho mob ua tau zoo.

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Cim npe nrov: Hepius Salbutamol 20mg CAS: {{18559-94-9}}}}}}}} {{{{{{} Cov chaw tsim khoom, cov chaw tsim khoom, Hoobkas