Taw qhia

Siab -Purity Peptide Hoobkas Qhuav Thiab Kev Thauj Mus Los

Txhim kho Zog Metabolism

Siab -Quality Peptides

Kev thauj mus los thoob ntiaj teb

Laboratory-Kev Tshawb Fawb Qib

Muaj nuj nqi ntau

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Khoom Description

Los ntawm qhov kev xav, Cardiogen feem ntau yog cais raws li luv - saw oligopeptide, feem ntau muaj li ntawm 2 txog 5 amino acids, nrog rau qhov hnyav molecular thiab cov qauv yooj yim. Cov qauv no muab cov ntaub so ntswg zoo permeability, tab sis kuj txiav txim siab nws cov metabolism sai hauv vivo. Nws feem ntau tshwm li dawb los yog tawm - cov hmoov dawb, yog yooj yim soluble hauv dej, thiab rhiab heev rau qhov kub thiab txias; yog li ntawd, nws feem ntau yuav tsum tau kub thiab lub teeb tiv thaiv thaum lub sij hawm cia thiab thauj.

Nyob rau theem ua haujlwm, kev tshawb fawb ntawm Cardiogen feem ntau tsom rau nws cov kev tswj hwm ntawm cardiomyocytes. Qee qhov kev sim hauv vitro tau pom tias hom peptide no tuaj yeem txhim kho lub zog metabolism ntawm cardiomyocytes los ntawm kev cuam tshuam mitochondrial kev ua ub no, yog li ua kom cov hlwb ua siab ntev rau hypoxia lossis kev ntxhov siab ib puag ncig rau qee qhov. Tsis tas li ntawd, qee qhov kev tshawb fawb qhia tias nws tuaj yeem koom nrog hauv kev tswj hwm cov protein qhia hauv cardiomyocytes, tshwj xeeb tshaj yog cov proteins uas cuam tshuam txog kev ua haujlwm ntawm lub cev thiab kho cell.

Nws yog ib qho tseem ceeb uas Cardiogen tsis siv nws cov teebmeem los ntawm kev txhawb nqa ib leeg xwb, tab sis ua haujlwm zoo li "cov teeb liab tswj." Nws tuaj yeem ua tiav tag nrho cov kev tswj hwm ntawm cov hlab plawv los ntawm kev cuam tshuam rau ntau txoj hauv kev hauv lub cev, xws li oxidative kev nyuaj siab teb txoj hauv kev lossis o -txoj kev cuam tshuam. Cov txheej txheem no kuj piav qhia vim li cas nws cov teebmeem feem ntau maj mam es tsis yog tam sim.

Hais txog kev ruaj ntseg, vim nws cov amino acid ntuj muaj pes tsawg leeg, Cardiogen tau yooj yim degraded los ntawm proteases hauv vivo, uas yog ob qho tib si kom zoo dua thiab muaj kev txwv. Ntawm qhov tod tes, tus yam ntxwv no txhais tau tias txo qis toxicity thiab tsawg dua kev pheej hmoo; ntawm qhov tod tes, nws kuj txwv lub sijhawm ntawm nws cov teebmeem. Yog li ntawd, hauv cov ntawv thov kev sim, cov tswv yim sib xws suav nrog kev siv cov khoom siv txuas ntxiv mus rau - tso tawm lossis tshuaj hloov kho kom ncua nws ib nrab - lub neej.

Hais txog nws daim ntawv thov kev cia siab, Cardiogen yog tam sim no tseem nyob rau hauv kev tshawb fawb theem. Nws tau nyiam qee qhov kev saib xyuas hauv cov ntaub so ntswg kho, kev tswj lub cev, thiab kev laus -txog kev tshawb fawb. Qee cov kws tshawb fawb tab tom sim muab nws nrog lwm cov peptides ua haujlwm los soj ntsuam cov teebmeem kev sib koom ua ke, uas muab cov tswv yim tshiab rau nws qhov kev nthuav dav yav tom ntej.

Zuag qhia tag nrho, Cardiogen sawv cev rau ib chav kawm ntawm kev tswj hwm peptides, uas yog nws cov qauv yooj yim, kev ua me me, thiab ntau yam - lub hom phiaj muaj peev xwm. Txawm hais tias cov kev tshawb fawb ntsig txog tseem tab tom ua tiav, nws cov txiaj ntsig kev tshawb fawb hauv plawv plawv- cov haujlwm ntsig txog yog maj mam tshwm sim. Nyob rau hauv lub neej yav tom ntej, nrog rau kev txhim kho ntawm peptide stability hloov kho thev naus laus zis thiab kev xa khoom, cov molecules no tuaj yeem pom muaj peev xwm ntau dua hauv ntau qhov chaw kho mob biomedical.