Cov ntsiab lus kev paub
Testosterone decanoate thiab Testosterone undecanoate yog ob qho tib si esterified cov ntaub ntawv ntawm testosterone, feem ntau yog siv hauv testosterone hloov kho (TRT) los kho cov txiv neej tsis tshua muaj testosterone. Qhov sib txawv ntawm ob cov tshuaj no feem ntau tshwm sim hauv cov hauv qab no:
### 1. **Chemical structure**
- **Testosterone decanoate**: fatty acid saw nrog 10 carbons nyob rau hauv molecule.
- **Testosterone undecanoate**: fatty acid saw nrog 11 carbons nyob rau hauv lub molecule.
Qhov sib txawv ntawm ester saw ntev ncaj qha cuam tshuam rau qhov tso tawm thiab cov yam ntxwv metabolic ntawm cov tshuaj.
### 2. ** Tso tawm thiab lub sijhawm ua haujlwm **
- ** Testosterone decanoate **:
- Lub sijhawm tso tawm sai dua, tab sis tseem yog ester ntev.
- Feem ntau siv ua ke nrog lwm yam esterified testosterone (xws li propionate lossis isocaproate), piv txwv li hauv kev npaj sib xyaw (xws li Sustanon).
- Ib nrab neej feem ntau yog 7-10 hnub, yuav tsum tau txhaj tshuaj ntau zaus (feem ntau ib zaug txhua 2-4 lub lis piam).
- ** Testosterone Undecanoate **:
- Nws yog ib qho qeeb tshaj plaws-tso testosterone esters paub txog hnub no.
- Nrog rau ib nrab-lub neej ntawm 18-21 hnub, kev txhaj tshuaj ntau zaus yog ib zaug txhua 10-14 lub lis piam, uas yog qhov tsim nyog rau cov neeg mob uas xav tau cov qib testosterone ntev ntev.
### 3. **Kev siv**
- ** Testosterone Decanoate **:
- Feem ntau txhaj tshuaj intramuscularly.
- Feem ntau siv hauv kev npaj ua ke, tsis yog ib leeg.
- ** Testosterone Undecanoate **:
- Yuav txhaj tshuaj intramuscularly lossis qhov ncauj (xws li Andriol). Kev npaj ntawm qhov ncauj yog nqus mus rau hauv cov kab mob lymphatic los ntawm chylomicrons, tsis txhob cuam tshuam thawj zaug ntawm lub siab, thiab siv tau yooj yim dua.
- Cov tshuaj txhaj tshuaj intramuscular ntev yog siv dav hauv kev kho mob ntawm cov tsis tshua muaj testosterone.
### 4. **Kev siv kho mob thiab kev qhia**
- Ob leeg yog siv rau kev hloov pauv testosterone, tab sis testosterone undecanoate yog qhov tsim nyog rau cov neeg mob uas xav tau kev txhaj tshuaj tsawg dua thiab ua haujlwm ntev ntev vim nws cov khoom ua haujlwm ntev.
- Testosterone decanoate feem ntau yog siv los ua ib feem ntawm kev sib xyaw ua ke los muab cov tshuaj ntshav nruab nrab cov tshuaj concentration saib xyuas.
### 5. **Side Effects**
- Cov kev mob tshwm sim ntawm ob qho tib si yog qhov zoo sib xws, suav nrog kev tuav dej, pob txuv, polycythemia, thiab lwm yam, uas muaj feem xyuam rau tus neeg mob cov koob tshuaj thiab kev kam rau tus kheej.
- Vim muaj qhov ruaj khov tso tawm nkhaus ntawm undecanoate ntau dua, cov kev tsis zoo tshwm sim los ntawm kev hloov pauv hauv cov ntshav cov tshuaj concentration feem ntau zam tau zoo dua.
### Cov ntsiab lus
- **Testosterone decanoate**: Tus nqi tso tawm sai dua, tsim nyog rau cov kev cai luv luv lossis kev kho ua ke.
- **Testosterone undecanoate**: Tus nqi tso tawm qeeb heev, haum rau cov neeg mob uas xav tau kev ua haujlwm ruaj khov mus ntev thiab txo qhov kev txhaj tshuaj ntau zaus.
