FierCE Zoo ARIMIDEX 1MG * 50

### Systemtic Qhia Txog Kev Ua Phem Ua Si Arimideex Capsules 1Mg

#### 1.} cov tshuaj tiv thaiv

** Fierce Hom Arimide 1Mg ** yog cov poj niam tsis muaj mob qog nqaij hlav - cov kab mob tsis muaj zog synthesis. Lub hom phiaj tseem ceeb hauv kev kho mob ntiaj teb

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#### 2. Cov Khoom Siv Hluav Taws Xob

1.}} me ntsis kev ua **

- anastrozole kev sib tw sib txawv

- Siab xaiv tau, tsis cuam tshuam rau cov synthesis ntawm adrenal cortex cov tshuaj hormones lossis cov qog cov qog lossis cov thyroid hormones.

{{0 {}} ** **

- ** Kev nqus tau **: Lub ncauj bioavailability yog li 83%-85%, thiab khoom noj tsis muaj qhov cuam tshuam ntawm kev nqus.

- ** TSIAJ ** PLASMA cov tshuaj tiv thaiv cov protein khi tau yog li 40%, thiab nws yog dav faib rau hauv lub cev .

- ** Metabolism **: metabolized rau cov khoom lag luam tsis ua haujlwm los ntawm daim siab cyp3A4, nrog ib nrab-lub neej, haum rau ib zaug pab nyiaj {}}

- ** ADCRETION **: 85% tau tawm los ntawm ob lub raum, thiab 11% yog ua tiav los ntawm cov quav {}}

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#### 3. lub cev thiab tshuaj lom neeg

{{0 {}}, cov qauv tshuaj **

- molecular cov mis: c₁₇h₁₉n₅

- molecular hnyav: 293.37 g / mol

- iUpac Npe: 2,2 '- [{{} (1h {} {} {}}} methylpropiononitrile)

{{0 {{}} ** Siv lub cev thiab tshuaj tsis zoo **

- ** Pom zoo ** ** dawb kom tawm-dawb crystalline hmoov {2.

- ** Melting taw tes **: {81-84℃(thawj qauv tshuaj).

- ** Solubility **: dej qis solubility (<0.1 mg/mL), easily soluble in organic solvents such as ethanol and acetone.

- ** STABLY **: KHW AT 25℃hauv lub kaw kaw cia ntawm lub teeb, nrog lub txee txee ntawm 36 lub hlis; Vaum rhiab, noo-pov thawj .

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#### 4. dosage daim ntawv thiab capsule tsim

{{0 {}}} ** tshuaj ntsiav sib xyaw **

- ** Cov ntsiab lus **: Aleaszole Micaszolized Granules (1MG / Capsule), sib xyaw nrog cov kab mob cellulose thiab lwm cov ntsiab lus hauv cov ntsiab lus tsis zoo.

- ** CYFSULE Plhaub **: Ua los ntawm HydroxyPropyyl Metylropenfose (HPMC), nws ua tau raws li cov neeg tsis noj zaub thiab ua xua}

{{0 {{}} ** xim thiab logo **

- ** Pom zoo ** Nws tau txais ob-xim tshuaj ntsiav, ** Blue Opaque Capsule lub cev ** thiab ** Cov tshuaj ntsuab dawb huv **}}

- ** ** CAPSULE Lub cev tau luam tawm nrog "Lub Cim Hluav Taws Xob" yog cim nrog cov "1mg" ntau npaum li cas los tiv thaiv kev siv tsis raug mob.

{{0 {}} ** Cov Specifications **

- Txuj ci txhuas-yas hlwv ntim, 10 cov ntsiav tshuaj ib phaj, 3 daim hlau ib lub thawv (30 ntsiav tshuaj ib lub thawv (30 ntsiav tshuaj / kem), nrog Desiccant .

- lub npov sab nraud siv cov lus cim nyiaj xaim hluav taws xob thiab los nrog ntau hom lus (suav nrog Brailille version) .

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#### 5. kev saib xyuas zoo thiab cov ntsiab lus tseem ceeb muag

1. ** Rov qab ua tau zoo dua **

- ** High Efficiency **: Cov chaw kuaj mob qhia tias qhov {{1} he} tus kab mob xyoo ua ntej yog 18% siab dua li ntawm tamoxifen (ATAC}}

- ** Tus kab hla qis-toxicity **: tsis cuam tshuam nrog mineralocorticoid synthesis, txo txoj kev pheej hmoo ntawm bypertension thiab edema.

{{0 {}} ** Kev Nyab Xeeb **

- ** Kev thev taus zoo **: Qhov tshwm sim ntawm kev sib raug zoo yog<5%, and common hot flashes (35%) and joint pain (28%) are mostly mild to moderate.

- ** Kev tswj hwm kab mob Osteoporosis ": Nws raug nquahu kom siv bisphosphonates hauv kev sib xyaw ua ke, thiab kev pheej hmoo ntawm cov pob txha pob txha tau txo los ntawm 30% piv nrog cov khoom thaum ntxov.

{{03.}} ** Tus Neeg Mob Yooj Yim **

- Ib qho kev tswj hwm ib zaug hauv ib hnub, ua raws li kev ua siab zoo; Tsis muaj kev txwv noj zaub mov noj, tuaj yeem coj ua ntej / tom qab noj mov .

- optimized capsule loj (18 hli ntev), yooj yim kom nqos, tus phooj ywg rau cov neeg mob laus

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#### 6. Ntau lawm txheej txheem thiab kev tswj hwm zoo

1.} ** Cov Qauv Raug Rau Ob

- Ua raws li FDA, EMA thiab ICH Q7 cov lus qhia tshwj xeeb, API purity ntau dua lossis sib npaug nrog 99{{15}} 8% (HPLC sim).

- Txais koob hmoov hnav granulation tshuab los xyuas cov ntsiab lus sib xyaw (RSD<2%).

2.} ** Kev ntsuas kev ruaj ntseg **

- Kev ntsuas kev nrawm (40℃/ 75% Rh) rau 6 lub hlis, cov khoom lag luam<0.2%, in line with ICH Q1A requirements.

- Dissolution: Release >85% tsis pub dhau 30 feeb (USP duav duav, Ph 6 . 8).

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#### 7. Kev ua lag luam txoj hauj lwm thiab hom nqi

{{01. ** Cov neeg hom phiaj **

- Thawj-kab adjuvant kev kho mob thiab kev kho mob siab heev ntawm postmenopausal er + / hey2-}}}}}}}

- cov neeg mob uas tiv taus tamoxifen lossis xav kom zam qhov kev pheej hmoo ntawm thrombosis .

2.} ** "Kev Sib Tw Rau Cov Kev Sib Tw **

- **Cost-effectiveness**: After the patent expires, the price of generic drugs is 30% lower than that of original drugs, and the medical insurance coverage rate is >90%.

- ** LAYIDE Kev nthuav dav **: Pom zoo hauv 50+ teb chaws, thiab cov ntsiab lus tau nthuav dav rau txiv neej mob cancer mis (rho tawm daim ntawv lo) {}}

{{03. ** Cov Mob Txhawb Pab Txhawb Nqa **

- Nco ntsoov nco txog cov tshuaj sab laj thiab cov kev pab cuam online thiab nyiaj txiag pab txhim kho kev kho ncua ntev mus ntxiv mus txuas ntxiv}

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#### 8. ceeb toom kev nyab xeeb thiab cov kev ceeb toom

- ** Cov teeb meem me me ** Thaum cev xeeb tub (Teratogenic muaj kev pheej hmoo), lub siab ua tsis zoo (cov menyuam-phgh c qib).

- ** Kev siv yeeb tshuaj **

- ** COV NTAUB NTAWV TSO CAI **: Basporine thiab cov pob txha tsis tu ncua, kev soj ntsuam lipid lipid lipid (LDL yuav nce ntxiv) {1}.

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#### 9. txoj kev txhim kho yav tom ntej

- ** Kev kho kev kho mob **: Tshawb nrhiav kev sib xyaw nrog CDK4 / 6 inibitors (xws li palbociclib) rau ntev ciaj sia ntawm cov neeg mob siab tshaj.

- ** Daim ntawv tshiab no tshiab **: Tsim cov kev hloov pauv ntawm lub plab zom zaws kom txo cov pa roj plab zom mov.

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### xaus

Kev tsiv dag rau Arimide cov khoom lag luam 1MG tau dhau los ua cov tshuaj tua kab mob {} Lub neej zoo dua rau cov neeg mob nyob thoob ntiaj teb {}}

Txhawb txoj kev them nyiaj

 

 

Peb txhawb ntau txoj kev them nyiaj

 

Tiv Tauj Peb

 

 

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Cim npe nrov: FierCE Zoo ARIMIDEX 1MG * 50, Tuam Tshoj Ua Siab Zoo Ua Siab Zoo ArimideX 1Mg * 50 Cov Khoom Siv, Chaw Tsim Tshuaj